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Team
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Koichi Yuki, M.D.

Principal Investigator

Dept of Immunology, Harvard Medical School

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Professor of Anesthesia

Harvard Medical School

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Clinical Senior Associate of Cardiac Anesthesia

Dept of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital 

 

Director of Cardiac Anesthesia Research

Boston Children's Hospital

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Associate Member

Broad Institute of MIT and Harvard

Dr. Koichi Yuki obtained his M.D. from the University of Tokyo, Japan in 1999. He finished his Surgical Internship at University of Hawaii in 2002 and his Anesthesia Residency at Massachusetts General Hospital in 2005. At Boston Children's Hospital, Dr. Yuki pursued two fellowship trainings: Pediatric Anesthesia in 2006 and Pediatric Cardiac Anesthesia in 2007.  Under Drs. Timothy Springer and Motomu Shimaoka (Immune Disease Institute), he completed a postdoctoral research fellowship in 2012.

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As a Board-Certified Anesthesiologist, Pediatric Cardiac Anesthesiology is Dr. Yuki's area of expertise.  He has been serving as an attending physician at Boston Children's Hospital since 2009. When not practicing as a clinician, he is a scientist who conducts research. His work aims to clarify how myeloid cells and systemic inflammation might cause organ injury in sepsis. His lab has also looked into the impact of anesthetics on perioperative immune function and postoperative outcomes. Dr. Yuki is also the Director of Cardiac Anesthesia Research at Boston Children's Hospital.  His  research has been funded by NIH grant since 2012.

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Dr. Yuki's Harvard Catalyst Profile:

https://connects.catalyst.harvard.edu/Profiles/display/Person/88546

 

Federal Grants Funding:

NIAID (R21AI185295) Jun 2025 - Jun 2027
Unravelling the role of aDb2 as a novel complement receptor in lung injury.

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NIGMS (R01GM148392) Feb 2023 - Dec 2026

CD11c as a novel target to improve neutrophil effector functions and sepsis outcome

Role: Principal Investigator: Koichi Yuki

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NICHD (R21HD109119) Aug 2022 - Jul 2024

The role of damage-associated molecular patterns in perioperative morbidities and mortalities of pediatric congenital heart diseases

Role: Principal Investigator: Koichi Yuki

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NIGMS (R01GM1276oo) May 2022 - Apr 2024

Surgical site infections and the role of anesthesia and bacterial ion transporters

Role: Principal Investigator: Koichi Yuki

 

NIAID (R21AI15886) Feb 2021 - Jan 2024 

Optimization of anesthetic/sedative regimen for pulmonary pathophysiology in cystic fibrosis patients 

Role: Principal Investigator: Koichi Yuki

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NICHD (R21HD099194) Apr 2020 - Mar 2023

Neutrophil-mediated multiple organ dysfunction during sepsis

Role Principal Investigators: Koichi Yuki & Sophia Koutsogiannaki

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NIGMS (R01GM118277) Apr 2016 - Mar 2022

The impact of anesthetic selection on sepsis outcome and its mechanism

Role: Principal Investigator: Koichi Yuki

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NIGMS (K08GM101345) Apr 2012 - Sep 2018

Immunomodulatory mechanism of volatile anesthetics

Role: Principal Investigator: Koichi Yuki

Members

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Sophia Koutsogiannaki, Ph.D.

Research Associate

Boston Children's Hospital

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Assistant Professor of Anaesthesia

Harvard Medical School

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Education: Aristotle University of Thessaloniki / Immunology

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Research Interests: Integrin and lung injury

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For more publications:

https://connects.catalyst.harvard.edu/Profiles/display/Person/147672​

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Xiaohui Han, R.N.

Laboratory Manager

Boston Children's Hospital

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Sirintip Swangwong, M.D.

Postdoctoral Research fellow
Boston Children’s Hospital

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For more publications:

https://connects.catalyst.harvard.edu/profiles/display/Person/226411

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Suguru Yamamoto, M.D

Research Fellow

Boston Children's Hospital​​​​​​​​

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Emma Tay

Student

Boston University

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Hannah Mcleod, B.S.

Student

Tufts Medical School​

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